Can PNs Prevent Ageing?

Polynucleotide (PN) treatments have revolutionised aesthetic medicine in recent years, offering patients looking to rejuvenate their complexion an alternative to what many have come to think of as more traditional treatments, such as Botox and dermal fillers.

Today I wanted to take the opportunity to dive a bit deeper into the science behind PNs and how this type of rejuvenating treatment can be used to prevent the signs of ageing.

What are PNs?

PNs are chains of individual nucleotides, that make up our DNA. PNs are involved in a number of biological processes, including the development of new, healthy skin cells.

The levels of collagen and elastin that our bodies are able to produce naturally decrease as we age, which leads to the development of fine lines, wrinkles, and sagging skin. However, PN treatments have the ability to kick-start the production of elastin and collagen, which we know are critical to maintaining both the firmness and elasticity of the skin.

The Role of PNs in Anti-Ageing

PN treatments are formulated using salmon or trout DNA, which, when filtered and purified, are well tolerated by the body. PN treatments are injected into the skin and can be used in an ultra-targeted way to minimise the appearance of lines, wrinkles, stretch marks, acne scarring, and more.

Please note that it is important to visit an experienced aesthetic practitioner with an understanding of facial anatomy in order to obtain optimal outcomes for any injectable treatment.

How PNs Work

When injected into the skin PNs can start working to rejuvenate the treatment area by interacting with skin cell receptors in order to promote cellular regeneration. During this process, new elastin and collagen fibres are produced, which can lead to firmer, smoother, more radiant looking skin. Healthy skin cells also have the ability to retain moisture, which can boost the skin's overall hydration levels and improve its texture.

Additionally, PNs have been shown to demonstrate anti-inflammatory properties and an ability to strengthen the skin barrier, including repairing damage caused by environmental factors, UV light, pollution and free radicals.

What Can PNs Treat?

As PN treatments successfully activate undifferentiated cells, which are able to differentiate to myofibroblasts and dermal cells, they can be used to effectively treat a number of different areas of the face and body.

Popular treatment areas include areas with acne scarring or stretch marks, areas displaying inflammatory skin concerns, including dermatitis and rosacea, and the delicate under eye area. PN treatments have also been shown to be effective in treating hair loss and restoring the skin's protective barrier.

Will My Results Last?

Unlike more traditional injectable treatments such as Botox and dermal fillers, it takes some time for the results of PN treatments to become visible. This is because PNs are working to restore skin health beneath the surface, which means that results will gradually become more noticeable in the 12 weeks following treatment.

As with any aesthetic treatment, it is important to visit a trusted practitioner who will develop a bespoke treatment plan based on your skin concerns and the outcomes you want to achieve. Some patients are happy with their results from a single PN treatment, while others opt for a course of several treatments spaced several weeks apart. In most cases, a maintenance treatment every six months is all that is required to maintain positive results.

If you would like to learn more about PNs or book a consultation with one of our experienced skin professionals, please reach out to us via email or phone at your earliest convenience.

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